BackgroundHemophagocytic lymphohistiocytosis (HLH) is a fatal immunological syndrome resulting from excessive production of inflammatory cytokines.The conventional therapies for HLH, which are based on cytotoxic agents, are not always efficacious and safe, especially in patients with severe immunodeficiency.Ruxolitinib, a strong inhibitor of Janus
Pathogens causing acute disease and death or lasting immunity require specific spatial or temporal processes to persist in populations.Host traits, such as maternally-derived antibody (MDA) and seasonal birthing affect infection maintenance within populations.Our study objective is to understand how viral and host traits lead to population level in
Crystallization is an important process, which possesses an undeniable role in many chemical industries.In recent years, significant endeavors have been made to increase the efficiency of this process via designing novel crystallizers.Development of numerical models and their efficient solutions is known as an important approach to justify the beha
Abstract Non-alcoholic fatty liver disease (NAFLD) constitutes a substantial proportion of cases among the non-obese population, yet it is frequently overlooked.Studies investigating the association between triglyceride-glucose (TyG)-related parameters (TyG-BMI, TyG-WC, TyG-WHtR) and NAFLD in non-obese individuals is limited.Thus, this study aims t